Outcomes of simultaneous kidney-pancreas transplantation in patients with type-I and type-II diabetes mellitus

Presenter: Hosein Shokouh-Amiri MD | Willis Knighton Medical Center Background: UNOS approved simultaneous kidney-pancreas transplantation (SKPT) for type-II diabetes mellitus (DM) in Oct 2014. In Jan 2015, we actively listed DM patients with ESRD or e-GFR ≤ 20 ml/min/m2 SKPT if they met the following criteria: age < 55 years, on insulin 1 unit/kg body weight, and a maximum allowable mass index (BMI 30 kg/m2). The two major advantages receiving as compared kidney transplant alone are much shorter waiting time usually better-quality kidney. There is limited data comparing outcomes of type-I versus DM. aim this study was to measure change volume SPKT since it compare death-censored 5-year graft patient survival between undergoing SKPT. Methods: We conducted retrospective chart-review from 2010 Nov 2020 collected demographics such age, gender, race. BMI, c-peptide, HbA1c, were noted pre-transplant 1-year post-transplant. Outcome variables included pre-and post-approval patients, pancreas grafts, survival. Student’s t-test continuous variables, Chi-square test categorical Mantel-Cox analysis done using SPSS. Results: As older [47.4 vs 40.2 p-value = 0.01] had higher BMI [32.0 26.7 kg/m2, eGFR [76.7 62.0 ml/min/1.73m2, 0.04] Among 89 SKPT, 18 (all DM) before approval 71 (41 after approval. This translated an increase 3.6/year 11.8/year (228% increase). no differences grafts Conclusion: Approval by led